Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949213 | 0.86 | SMN1; SMN2 (0.39) | SCDNPC1RAB9AKDM4EMAPT | |
| SCHEMBL8949336 | 0.73 | KDM4E (0.41) | SCDNPC1RAB9AKDM4EMAPT | |
| SCHEMBL4958152 | 0.67 | TSHR (0.54) | SCDNPC1RAB9AKDM4ECYP19A1 | |
| SCHEMBL18764736 | 0.66 | ALDH1A1 (0.42) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10566878 | 0.66 | ALDH1A1 (0.52) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL1903612 | 0.65 | CYP3A4 (0.50) | MAPTSMN1; SMN2LMNAPOLBGRIN2D | |
| SCHEMBL28679512 | 0.65 | GABRA2 (0.55) | NPC1RAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL12604388 | 0.64 | SCD (0.74) | SCDKDM4EMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL5990662 | 0.64 | ALDH1A1 (0.47) | KDM4EMAPTGABRG2GABRB3GABRA5 | |
| SCHEMBL30739186 | 0.63 | SMN1; SMN2 (0.39) | SCDCYP19A1SMN1; SMN2GABRA5GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |