Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PRCP | P42785 | 2/20 | 0.46 |
| ▸ | GRN | P28799 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 5/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443983 | 0.83 | GAA (0.54) | SMN1; SMN2GAAHPGDPRCPCNR1 | |
| SCHEMBL11298431 | 0.79 | GPR139 (0.48) | SMN1; SMN2GAAHPGDPRCPGPR139 | |
| SCHEMBL9439080 | 0.77 | GAA (0.48) | SMN1; SMN2GAAHPGDPRCPCNR1 | |
| SCHEMBL7897298 | 0.77 | SMN1; SMN2 (0.69) | SMN1; SMN2GAAHPGDPRCPGPR139 | |
| SCHEMBL8444499 | 0.76 | LMNA (0.47) | LMNAMEN1KMT2A | |
| SCHEMBL9371746 | 0.76 | FFAR2 (0.45) | SMN1; SMN2GAAHPGDPRCPGRN | |
| SCHEMBL7674958 | 0.74 | GAA (0.58) | SMN1; SMN2GAAHPGDPRCPCNR1 | |
| SCHEMBL22279548 | 0.74 | GAA (0.58) | SMN1; SMN2GAAHPGDPRCPGPR139 | |
| SCHEMBL2651517 | 0.74 | GAA (0.58) | SMN1; SMN2GAAHPGDPRCPCNR1 | |
| SCHEMBL6392377 | 0.74 | GAA (0.58) | SMN1; SMN2GAAHPGDPRCPGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |