Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 8/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 8/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.39 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.39 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949422 | 0.99 | MEN1 (0.41) | ITGB3ITGA2BF2ST14PRSS1 | |
| SCHEMBL8949406 | 0.92 | MAPK14 (0.43) | ITGB3ITGA2BF2ST14PRSS1 | |
| SCHEMBL8949300 | 0.92 | ITGB3 (0.39) | ITGB3ITGA2BF2ST14PRSS1 | |
| SCHEMBL8949089 | 0.90 | ITGB3 (0.40) | ITGB3ITGA2BF2ST14PRSS1 | |
| Hydrochloric Acid SCHEMBL8949020 | 0.89 | TMPRSS15 (0.39) | ITGB3ITGA2BF2ST14PRSS1 | |
| Hydrochloric Acid SCHEMBL8949012 | 0.89 | MAPK13 (0.40) | ITGB3ITGA2BF2ST14PRSS1 | |
| Hydrochloric Acid SCHEMBL8949212 | 0.82 | TMPRSS15 (0.40) | ITGB3ITGA2BF2ST14PRSS1 | |
| Hydrochloric Acid SCHEMBL8949417 | 0.82 | MAPK14 (0.42) | F2ST14PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8949151 | 0.81 | TMPRSS15 (0.37) | ITGB3ITGA2BF2ST14PRSS1 | |
| SCHEMBL8949341 | 0.81 | KLK7 (0.45) | ITGB3ITGA2BF2ST14PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |