Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28237020 | 0.79 | NPSR1 (0.44) | NPSR1MAPTALDH1A1CA12CA9 | |
| SCHEMBL29025199 | 0.69 | MAPT (0.47) | NPSR1MAPTALDH1A1CA12CA9 | |
| SCHEMBL8949893 | 0.68 | CA9 (0.40) | NPSR1MAPTALDH1A1CA12CA9 | |
| SCHEMBL1297642 | 0.67 | ALDH1A1 (0.53) | NPSR1MAPTALDH1A1CA12CA9 | |
| SCHEMBL9138295 | 0.65 | CA9 (0.52) | NPSR1MAPTALDH1A1CA12CA9 | |
| Phosphoric Acid SCHEMBL29169622 | 0.65 | ALDH1A1 (0.50) | PTPN1MAPTALDH1A1CA12CA9 | |
| SCHEMBL28064849 | 0.65 | MAPT (0.40) | NPSR1MAPTALDH1A1CA12CA9 | |
| SCHEMBL5572988 | 0.65 | ALDH1A1 (0.50) | NPSR1MAPTALDH1A1S1PR2S1PR4 | |
| SCHEMBL29740904 | 0.65 | ALDH1A1 (0.50) | NPSR1MAPTALDH1A1S1PR2S1PR4 | |
| SCHEMBL8949636 | 0.65 | TSHR (0.50) | PTPN1CA12CA9TSHRPTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574024-A | Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | EBETINO FRANK H (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0298553-B1 | METHYLENE PHOSPHONOALKYLPHOSPHINATES, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | Norwich Eaton Pharmaceuticals, Inc. (US) | 1992-01-15 | — | — | EP | disclosed |