Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949745 | 0.75 | TSHR (0.52) | NPC1RAB9AALDH1A1MAPK1FDPS | |
| SCHEMBL8949893 | 0.71 | CA9 (0.40) | ALDH1A1FDPSSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9652020 | 0.70 | FFAR1 (0.40) | FFAR1NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL29195442 | 0.70 | FFAR1 (0.40) | FFAR1NPC1RAB9AALDH1A1MAPK1 | |
| Butane SCHEMBL8826144 | 0.70 | FFAR1 (0.40) | FFAR1NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL18911584 | 0.69 | FFAR1 (0.50) | FFAR1NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL4591759 | 0.69 | FFAR1 (0.50) | FFAR1NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL8949883 | 0.69 | — | — | |
| Methylphenylsulfide SCHEMBL8949917 | 0.67 | KCNH2 (0.35) | NPC1RAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL2513707 | 0.66 | ALDH1A1 (0.62) | FFAR1NPC1RAB9AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574024-A | Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism | EBETINO FRANK H (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0298553-B1 | METHYLENE PHOSPHONOALKYLPHOSPHINATES, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | Norwich Eaton Pharmaceuticals, Inc. (US) | 1992-01-15 | — | — | EP | disclosed |