Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL8826144 | 0.79 | FFAR1 (0.40) | FFAR1ALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL9638244 | 0.74 | MEN1 (0.33) | NPC1KMT2AMEN1MAPT | |
| SCHEMBL9637977 | 0.71 | MAPT (0.42) | ALDH1A1MAPK1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8949914 | 0.70 | FFAR1 (0.38) | FFAR1ALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL15572774 | 0.66 | HPGD (0.35) | FFAR1ALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL15571917 | 0.66 | HPGD (0.35) | FFAR1ALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL15572570 | 0.66 | HPGD (0.35) | FFAR1ALDH1A1MAPK1KMT2ARECQL | |
| SCHEMBL10401993 | 0.66 | FFAR1 (0.54) | FFAR1ALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL15572456 | 0.66 | HPGD (0.35) | FFAR1ALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL3131963 | 0.66 | ALDH1A1 (0.57) | FFAR1ALDH1A1MAPK1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339237-B1 | PHENOL SUBSTITUTED GEM-DIPHOSPHONATE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1992-12-30 | — | — | EP | claimed |