SCHEMBL4591759

SCHEMBL4591759

O=P(O)(O)CSc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.50
ALDH1A1 P00352 3/20 0.48
MAPK1 P28482 1/20 0.48
FDPS P14324 4/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
RECQL P46063 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CFTR P13569 1/20 0.41
SRC P12931 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA5A P35218 1/20 0.41
PTPN1 P18031 1/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18911584 1.00 FFAR1 (0.50) FFAR1ALDH1A1MAPK1FDPSNPC1
SCHEMBL23521591 0.80 CA2 (0.47) ALDH1A1NPC1RAB9ARECQLSMN1; SMN2
SCHEMBL23521611 0.78 MMP2 (0.55) ALDH1A1FDPSRAB9ASMN1; SMN2MEN1
SCHEMBL16346391 0.78 LMNA (0.45) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL2513707 0.78 ALDH1A1 (0.62) FFAR1ALDH1A1MAPK1FDPSNPC1
SCHEMBL23521586 0.78 CA12 (0.41) ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL23521612 0.78 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2MEN1KMT2ACA2
SCHEMBL9636826 0.77 FDPS (0.47) ALDH1A1FDPSNPC1RAB9ASMN1; SMN2
SCHEMBL23521599 0.77 ACP3 (0.44) MAPK1SMN1; SMN2
SCHEMBL23521610 0.77 CA12 (0.44) ALDH1A1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1799638-B1 PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES CIBA HOLDING INC (CH) 2008-07-30 EP claimed
CN-106165175-B High molecular electrolyte composition and polyelectrolyte membrane, film electrode composite element and the polymer electrolyte fuel cell for using it 东丽株式会社 2019-11-08 CN disclosed
US-10103401-B2 Polymer electrolyte composition and polymer electrolyte membrane, polymer electrolyte membrane with catalyst layer, membrane electrode assembly, and polymer electrolyte fuel cell each using the same TORAY INDUSTRIES, INC. (JP) 2018-10-16 US disclosed
EP-3131145-B1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME TORAY INDUSTRIES (JP) 2018-09-05 EP disclosed
US-20170125832-A1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE WITH CATALYST LAYER, MEMBRANE ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL EACH USING THE SAME TORAY INDUSTRIES, INC. (JP) 2017-05-04 US disclosed
EP-3131145-A1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME Toray Industries, Inc. (JP) 2017-02-15 EP disclosed
CN-106165175-A High molecular electrolyte composition and use its polyelectrolyte membrane, film electrode composite element and polymer electrolyte fuel cell 东丽株式会社 2016-11-23 CN disclosed
CN-101484977-B Tio2 nanostructures, membranes and films, and applications of same UNIV ARKANSAS TECHNOLOGY DEV F 2012-12-05 CN disclosed
CN-101668584-A TiO2Nanostructures, films and thin layers and methods of making the same UNIV ARKANSAS TECHNOLOGY DEV F 2010-03-10 CN disclosed
CN-101484977-A Tio2 nanostructures, membranes and films, and applications of same UNIV ARKANSAS TECHNOLOGY DEV F (US) 2009-07-15 CN disclosed