Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 7/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872938 | 0.92 | ABL1 (0.38) | ABL1MAP4K1ITGB1ITGA4ADAM17 | |
| SCHEMBL8872200 | 0.92 | ABL1 (0.38) | ABL1MAP4K1ITGB1ITGA4ADAM17 | |
| SCHEMBL8874542 | 0.89 | BDKRB1 (0.39) | ABL1MAP4K1ITGB1ITGA4ADAM17 | |
| SCHEMBL8872711 | 0.86 | LMNA (0.35) | ABL1ITGB1ITGA4ADAM17MYC | |
| SCHEMBL8873694 | 0.86 | LMNA (0.35) | ABL1MAP4K1ITGB1ITGA4ADAM17 | |
| SCHEMBL8872985 | 0.85 | ABL1 (0.37) | ABL1MAP4K1ITGB1ITGA4ADAM17 | |
| SCHEMBL8958444 | 0.83 | WNT3A (0.37) | ABL1MAP4K1 | |
| SCHEMBL8958388 | 0.83 | WNT3A (0.37) | ABL1MAP4K1GSK3AGSK3B | |
| SCHEMBL8879710 | 0.78 | BDKRB1 (0.39) | BDKRB1 | |
| SCHEMBL8873195 | 0.78 | BDKRB1 (0.39) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5557002-A | Process for the preparation of biphenyl containing intermediates useful in making angiotensin II receptor antagonists | EISAI CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |