Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 3/20 | 0.37 |
| ▸ | BCL2 | P10415 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 7/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958444 | 0.91 | WNT3A (0.37) | WNT3ABCL2MCL1GRM5MAP4K1 | |
| SCHEMBL8872938 | 0.91 | ABL1 (0.38) | BCL2MCL1MAP4K1ABL1GSK3A | |
| SCHEMBL8958497 | 0.88 | LMNA (0.36) | WNT3ABCL2MCL1GRM5MAP4K1 | |
| SCHEMBL8958623 | 0.85 | LMNA (0.36) | WNT3ABCL2MCL1GRM5MAP4K1 | |
| SCHEMBL8949946 | 0.83 | ABL1 (0.39) | MAP4K1ABL1GSK3AGSK3B | |
| SCHEMBL8872200 | 0.81 | ABL1 (0.38) | BCL2MCL1MAP4K1ABL1GSK3A | |
| SCHEMBL8958543 | 0.81 | WNT3A (0.38) | WNT3AGRM5CD274XDHCYP19A1 | |
| SCHEMBL8873195 | 0.80 | BDKRB1 (0.39) | — | |
| SCHEMBL8873694 | 0.79 | LMNA (0.35) | BCL2MCL1MAP4K1ABL1GSK3A | |
| SCHEMBL8874542 | 0.77 | BDKRB1 (0.39) | MAP4K1ABL1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |