Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950339 | 0.82 | CA2 (0.41) | SMN1; SMN2CA2CA4TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL8950235 | 0.80 | CA2 (0.68) | SMN1; SMN2CA2CA4TSHRHIF1A | |
| SCHEMBL8950119 | 0.76 | CMA1 (0.32) | KDM4EKMT2AMAPTPDE1BMEN1 | |
| SCHEMBL5755331 | 0.72 | SMN1; SMN2 (1.00) | SMN1; SMN2TSHRHIF1AEPAS1KDM4E | |
| SCHEMBL28455980 | 0.69 | SMN1; SMN2 (0.90) | SMN1; SMN2TSHRHIF1AEPAS1KDM4E | |
| SCHEMBL28577542 | 0.67 | SMN1; SMN2 (0.85) | SMN1; SMN2TSHRHIF1AEPAS1KDM4E | |
| SCHEMBL25045759 | 0.64 | SMN1; SMN2 (0.68) | SMN1; SMN2TSHRHIF1AEPAS1KDM4E | |
| SCHEMBL28583600 | 0.63 | SMN1; SMN2 (0.77) | SMN1; SMN2TSHRHIF1AEPAS1KDM4E | |
| SCHEMBL26098259 | 0.63 | SMN1; SMN2 (0.76) | SMN1; SMN2TSHRHIF1AEPAS1KDM4E | |
| SCHEMBL8950201 | 0.63 | HTT (0.43) | SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | disclosed |