Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950133 | 0.83 | CA2 (0.36) | CA2CA4KMT2AHRH3MAPK1 | |
| SCHEMBL8950219 | 0.82 | SMN1; SMN2 (0.53) | CA2CA4KMT2ASIGMAR1CYP2D6 | |
| SCHEMBL8950382 | 0.79 | CA2 (0.62) | CA2CA4HRH3LMNA | |
| Hydrochloric Acid SCHEMBL8950454 | 0.78 | CA2 (0.61) | CA2CA4HRH3LMNA | |
| SCHEMBL8950469 | 0.77 | KMT2A (0.39) | CA2CA4KMT2AHRH3ALDH1A1 | |
| SCHEMBL9058336 | 0.77 | HTT (0.36) | KMT2AADORA2BHRH3MAPK1ALDH1A1 | |
| SCHEMBL8950389 | 0.70 | PTGER4 (0.34) | ADORA2BMAPK1ALDH1A1CYP1A2TSHR | |
| SCHEMBL8950314 | 0.68 | CA2 (0.57) | CA2CA4HRH3LMNA | |
| SCHEMBL8950201 | 0.66 | HTT (0.43) | KMT2AHRH3ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8950455 | 0.64 | CA2 (0.61) | CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | disclosed |