Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | LDHB | P07195 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950185 | 0.89 | SMN1; SMN2 (0.47) | MAPTKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8950295 | 0.73 | CHRNA7 (0.45) | MAPTSMN1; SMN2ALDH1A1TP53TSHR | |
| SCHEMBL9709296 | 0.71 | OPRL1 (0.44) | MAPTKMT2ASMARCA2SMARCA4PBRM1 | |
| SCHEMBL11808470 | 0.70 | PBRM1 (0.55) | MAPTKMT2ASMARCA2SMARCA4PBRM1 | |
| SCHEMBL10376869 | 0.69 | ABCB1 (0.48) | MAPTKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11225362 | 0.69 | MAPT (0.40) | MAPTSMARCA2SMARCA4PBRM1ALDH1A1 | |
| SCHEMBL8950429 | 0.68 | ALDH1A1 (0.46) | MAPTKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL20606723 | 0.67 | OPRL1 (0.60) | MAPTKMT2ASMARCA2SMARCA4PBRM1 | |
| SCHEMBL1943987 | 0.67 | SMARCA2 (0.45) | MAPTKMT2ASMARCA2SMARCA4PBRM1 | |
| SCHEMBL13706924 | 0.67 | SMARCA2 (0.45) | MAPTKMT2ASMARCA2SMARCA4PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577629-B1 | NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS | CIBA GEIGY AG (CH) | 1996-06-26 | — | — | EP | claimed |
| EP-0577629-B1 | NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS | CIBA GEIGY AG (CH) | 1996-06-26 | — | — | EP | disclosed |
| US-5506193-A | Herbicidally, acaricidally and insecticidally active pyrazolidine compounds | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |
| US-5494890-A | FOR CONTROLLING WEEDS, INSECTS, MITES | CIBA-GEIGY CORPORATION (US) | 1996-02-27 | — | — | US | disclosed |