Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950233 | 0.89 | MAPT (0.41) | SMN1; SMN2TSHRMAPTMAPK1NSD2 | |
| SCHEMBL8950295 | 0.80 | CHRNA7 (0.45) | SMN1; SMN2TSHRMAPTALDH1A1KDM4E | |
| SCHEMBL8950429 | 0.74 | ALDH1A1 (0.46) | TSHRHPGDMAPTALDH1A1KDM4E | |
| SCHEMBL9536702 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHRHPGDAADATNSD2 | |
| SCHEMBL16562616 | 0.73 | — | — | |
| SCHEMBL8950527 | 0.72 | ALDH1A1 (0.46) | SMN1; SMN2TSHRMAPK1ALDH1A1KDM4E | |
| SCHEMBL16562484 | 0.72 | ALDH1A1 (0.30) | ALDH1A1POLB | |
| SCHEMBL8950369 | 0.71 | LMNA (0.43) | TSHRMAPTMAPK1ALDH1A1MEN1 | |
| SCHEMBL16562608 | 0.69 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL9482529 | 0.68 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDMAPTMAPK1AADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577629-B1 | NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS | CIBA GEIGY AG (CH) | 1996-06-26 | — | — | EP | claimed |
| EP-0577629-B1 | NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS | CIBA GEIGY AG (CH) | 1996-06-26 | — | — | EP | disclosed |
| US-5506193-A | Herbicidally, acaricidally and insecticidally active pyrazolidine compounds | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |
| US-5494890-A | FOR CONTROLLING WEEDS, INSECTS, MITES | CIBA-GEIGY CORPORATION (US) | 1996-02-27 | — | — | US | disclosed |
| EP-0577629-A1 | NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS. | CIBA GEIGY AG (CH) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992016510-A1 | NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS | CIBA-GEIGY AG (CH) | 1992-10-01 | — | — | WO | disclosed |