Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950370 | 0.85 | KDM1A (0.32) | LOXKDM1AL3MBTL1ALDH1A1 | |
| SCHEMBL8950419 | 0.84 | CA2 (0.52) | CA2CA4 | |
| SCHEMBL9057829 | 0.78 | KDM1A (0.37) | CA2LOXKDM1AL3MBTL1ALDH1A1 | |
| SCHEMBL8950392 | 0.75 | CA2 (0.47) | CA2CA4 | |
| Hydrochloric Acid SCHEMBL9094229 | 0.73 | CA2 (0.40) | CA2CA4 | |
| SCHEMBL8950293 | 0.73 | CA2 (0.43) | CA2CA4 | |
| Hydrochloric Acid SCHEMBL8950381 | 0.72 | CA2 (0.42) | CA2CA4 | |
| SCHEMBL7941096 | 0.72 | CA2 (0.39) | CA2CA4 | |
| Hydrochloric Acid SCHEMBL8950390 | 0.71 | CA2 (0.46) | CA2CA4 | |
| Hydrochloric Acid SCHEMBL8950394 | 0.71 | CA2 (0.46) | CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | disclosed |