Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950325 | 0.85 | CA2 (0.38) | KDM1AL3MBTL1LOXALDH1A1 | |
| SCHEMBL8950328 | 0.82 | CA2 (0.31) | — | |
| SCHEMBL9115082 | 0.80 | KDM1A (0.34) | KDM1AL3MBTL1LOXALDH1A1THRB | |
| SCHEMBL8950595 | 0.78 | CA2 (0.33) | — | |
| SCHEMBL8950622 | 0.77 | — | — | |
| SCHEMBL8950362 | 0.76 | CA2 (0.35) | ALDH1A1 | |
| SCHEMBL8950316 | 0.74 | CA2 (0.35) | — | |
| SCHEMBL9057829 | 0.64 | KDM1A (0.37) | KDM1AL3MBTL1LOXALDH1A1THRB | |
| SCHEMBL7938911 | 0.62 | CA2 (0.47) | — | |
| SCHEMBL9058369 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | disclosed |