Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192543 | 0.83 | SMN1; SMN2 (0.46) | L3MBTL1HPGDCES1SMN1; SMN2HTT | |
| SCHEMBL22420907 | 0.83 | SMN1; SMN2 (0.47) | L3MBTL1HPGDCES1SMN1; SMN2HTT | |
| SCHEMBL11886413 | 0.83 | SMN1; SMN2 (0.46) | L3MBTL1HPGDCES1SMN1; SMN2HTT | |
| SCHEMBL788630 | 0.83 | SMN1; SMN2 (0.46) | L3MBTL1HPGDCES1SMN1; SMN2HTT | |
| SCHEMBL15449619 | 0.79 | SMN1; SMN2 (0.43) | L3MBTL1HPGDCES1SMN1; SMN2HTT | |
| SCHEMBL13130682 | 0.79 | SMN1; SMN2 (0.43) | L3MBTL1HPGDCES1SMN1; SMN2HTT | |
| SCHEMBL14879146 | 0.79 | SMN1; SMN2 (0.47) | L3MBTL1HPGDCES1SMN1; SMN2HTT | |
| SCHEMBL12101822 | 0.76 | LMNA (0.55) | L3MBTL1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL4418793 | 0.76 | LMNA (0.55) | L3MBTL1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL4418795 | 0.76 | LMNA (0.55) | L3MBTL1SMN1; SMN2HTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595364-B1 | Benz[e]indene derivatives and a process for preparing them as well as medicaments containing them and the use of them | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1996-07-24 | — | — | EP | disclosed |