Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13130690 | 0.90 | ALDH1A1 (0.51) | L3MBTL1HPGDALDH1A1MAPTKMT2A | |
| SCHEMBL11886413 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1HPGDHTTALDH1A1 | |
| SCHEMBL10192543 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1HPGDHTTALDH1A1 | |
| SCHEMBL788630 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1HPGDHTTALDH1A1 | |
| SCHEMBL8950340 | 0.79 | L3MBTL1 (0.47) | SMN1; SMN2L3MBTL1HPGDHTTALDH1A1 | |
| SCHEMBL18608898 | 0.78 | MAPT (0.41) | SMN1; SMN2L3MBTL1HTTALDH1A1MAPT | |
| SCHEMBL18590268 | 0.76 | NPC1 (0.36) | SMN1; SMN2L3MBTL1HPGDHTTALDH1A1 | |
| SCHEMBL22420907 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1HPGDHTTALDH1A1 | |
| SCHEMBL15449619 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL1HPGDHTTALDH1A1 | |
| SCHEMBL13130689 | 0.73 | MEN1 (0.37) | SMN1; SMN2HTTMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563732-B2 | Oxyimino compounds and the use thereof | SHIONOGI & CO., LTD. (JP) | 2013-10-22 | — | — | US | disclosed |
| US-20100240703-A1 | OXYIMINO COMPOUNDS AND THE USE THEREOF | PURDUE PHARMA L.P. | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240703-A1 | OXYIMINO COMPOUNDS AND THE USE THEREOF | CACNA1A, CACNA1S, OPRM1 | SMN1; SMN2 476/4885L3MBTL1 1643/4885HPGD 605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.