Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 14/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12101822 | 1.00 | LMNA (0.55) | LMNAMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL4418793 | 1.00 | LMNA (0.55) | LMNAMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL5189232 | 0.90 | LMNA (0.68) | LMNAMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL12609515 | 0.90 | LMNA (0.68) | LMNAMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL12609477 | 0.90 | LMNA (0.63) | LMNAMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL92004 | 0.81 | MAPT (0.67) | LMNAMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL12609462 | 0.80 | MAPT (0.46) | LMNAMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL12609456 | 0.80 | MAPT (0.54) | LMNAMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL12609463 | 0.78 | HTT (0.58) | MAPTKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL9411070 | 0.78 | MAPT (0.38) | LMNAMAPTL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720823-B1 | NEW PROCESS FOR THE SYNTHESIS OF SUBSTITUTED ALPHA-AMINOIDAN DERIVATIVES | ZACH SYSTEM (FR) | 2009-08-26 | — | — | EP | disclosed |
| US-7456320-B2 | Process for the synthesis of substituted alpha-aminoindan derivatives | ZACH SYSTEM (FR) | 2008-11-25 | — | — | US | disclosed |
| US-20070191640-A1 | Process for the synthesis of substituted alpha-aminoindan derivatives | PPG-SIPSY (FR) | 2007-08-16 | — | — | US | disclosed |
| EP-1797030-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF INDANYLAMINE OR AMINOTETRALIN DERIVATIVES AND NOVEL INTERMEDIATES | Teva Pharmaceuticals USA, Inc. (US) | 2007-06-20 | — | — | EP | disclosed |
| EP-1720823-A1 | NEW PROCESS FOR THE SYNTHESIS OF SUBSTITUTED ALPHA-AMINOIDAN DERIVATIVES | PPG-Sipsy (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2006029135-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF INDANYLAMINE OR AMINOTETRALIN DERIVATIVES AND NOVEL INTERMEDIATES | TEVA PHARMACEUTICAL USA, INC (US) | 2006-03-16 | — | — | WO | disclosed |
| EP-1574498-A1 | Process for the synthesis of substituted alpha-aminoindan derivatives | PPG-Sipsy (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2005082838-A1 | NEW PROCESS FOR THE SYNTHESIS OF SUBSTITUTED ALPHA -AMINOINDAN DERIVATIVES | PPG-SIPSY (FR) | 2005-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191640-A1 | Process for the synthesis of substituted alpha-aminoindan derivatives | ALDH7A1, ALAD, ASPH | LMNA 1290/4885MAPT 4049/4885L3MBTL1 4778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.