Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 11/20 | 0.36 |
| ▸ | GABRD | O14764 | 11/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 11/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 11/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 11/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 11/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 11/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 11/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 11/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 11/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 11/20 | 0.36 |
| ▸ | GABRE | P78334 | 11/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 11/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 11/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 11/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 11/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950610 | 0.82 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950400 | 0.73 | GABRP (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950509 | 0.73 | GABRP (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950463 | 0.66 | ALDH1A1 (0.30) | ALDH1A1TP53HTT | |
| SCHEMBL9677195 | 0.64 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL25072706 | 0.62 | ALDH1A1 (0.41) | ALDH1A1TP53HTT | |
| SCHEMBL9636686 | 0.60 | GABRP (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950588 | 0.59 | — | — | |
| Perchlorate SCHEMBL10654628 | 0.58 | ALDH1A1 (0.35) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9636563 | 0.57 | KDM1A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502073-A | INSECTICIDES OR ANTHELMINTICS | THE WELLCOME FOUNDATION (GB) | 1996-03-26 | — | — | US | disclosed |
| EP-0294229-A2 | Novel heterocyclic pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-12-07 | — | — | EP | disclosed |