SCHEMBL8950463

SCHEMBL8950463

CC(C)(C)C1CS[C@@](C)(c2ccc(Br)cc2)[S+]([O-])C1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8950456 0.74 ALDH1A1 (0.32) ALDH1A1TP53HTT
SCHEMBL9676401 0.68 ALDH1A1 (0.30) ALDH1A1TP53HTT
SCHEMBL8950530 0.68 KDM1A (0.33) ALDH1A1TP53HTT
SCHEMBL9677787 0.68 ALDH1A1 (0.30) ALDH1A1TP53HTT
SCHEMBL9676218 0.68 ALDH1A1 (0.30) ALDH1A1TP53HTT
SCHEMBL9677465 0.68 ALDH1A1 (0.30) ALDH1A1TP53HTT
SCHEMBL10654833 0.68 GABRP (0.38) ALDH1A1TP53HTT
SCHEMBL9678948 0.67
SCHEMBL9677269 0.67 GABRP (0.31)
SCHEMBL8950432 0.66 GABRP (0.36) ALDH1A1TP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5502073-A INSECTICIDES OR ANTHELMINTICS THE WELLCOME FOUNDATION (GB) 1996-03-26 US disclosed
EP-0294229-A2 Novel heterocyclic pesticidal compounds THE WELLCOME FOUNDATION LIMITED (GB) 1988-12-07 EP disclosed