Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950339 | 0.80 | CA2 (0.41) | ALDH1A1CA2CA4MAPK1 | |
| SCHEMBL8950389 | 0.79 | PTGER4 (0.34) | GAAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL9058210 | 0.72 | KDM4E (0.30) | GAAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL8950606 | 0.72 | CA2 (0.36) | GAAALDH1A1MAPTCA2CA4 | |
| SCHEMBL8950119 | 0.67 | CMA1 (0.32) | GAAALDH1A1MAPTKDM4E | |
| SCHEMBL8950476 | 0.67 | CA2 (0.45) | CA2CA4 | |
| SCHEMBL3585070 | 0.67 | CA2 (0.47) | GAAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL3577810 | 0.67 | CA2 (0.47) | GAAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL3586845 | 0.67 | CA2 (0.47) | GAAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL12603535 | 0.66 | TDP1 (0.41) | GAAALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | disclosed |