Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950208 | 0.81 | CA2 (0.33) | CA2CA4 | |
| SCHEMBL8950361 | 0.80 | LMNA (0.38) | CA2NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL22309076 | 0.56 | ALDH1A1 (0.49) | RAB9AMAPTALDH1A1P2RX7KMT2A | |
| 1,4-Dimethoxybenzene SCHEMBL28544369 | 0.55 | CA1 (0.69) | CA2GAANPC1RAB9AMAPT | |
| SCHEMBL10515467 | 0.54 | NPC1 (0.57) | CA2GAANPC1RAB9AMAPT | |
| SCHEMBL6358558 | 0.54 | CA12 (0.53) | CA2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL27329 | 0.54 | IDO1 (0.58) | CA2SMN1; SMN2ALDH1A1HTTCYP3A4 | |
| SCHEMBL4181089 | 0.54 | IDO1 (0.58) | CA2SMN1; SMN2ALDH1A1HTTCYP3A4 | |
| SCHEMBL717969 | 0.53 | RAB9A (0.61) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23728137 | 0.53 | ALDH1A1 (0.42) | CA2GAANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | disclosed |