Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BIRC2 | Q13490 | 6/20 | 0.42 |
| ▸ | BIRC3 | Q13489 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.41 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896284 | 0.86 | ALDH1A1 (0.43) | XIAPALDH1A1LMNAMAPTBIRC2 | |
| SCHEMBL895256 | 0.85 | ALDH1A1 (0.45) | XIAPALDH1A1LMNAMAPTBIRC2 | |
| SCHEMBL10066063 | 0.83 | OPRM1 (0.51) | ALDH1A1LMNAMAPT | |
| SCHEMBL10082409 | 0.83 | OPRM1 (0.51) | ALDH1A1LMNAMAPT | |
| SCHEMBL3439008 | 0.83 | XIAP (0.52) | XIAPALDH1A1LMNAMAPTBIRC2 | |
| SCHEMBL895869 | 0.83 | XIAP (0.52) | XIAPBIRC2BIRC3 | |
| Hydrochloric Acid SCHEMBL895599 | 0.82 | OPRM1 (0.51) | ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL895597 | 0.82 | OPRM1 (0.51) | ALDH1A1LMNAMAPT | |
| SCHEMBL10066062 | 0.81 | XIAP (0.55) | XIAPBIRC2BIRC3F2 | |
| SCHEMBL10081797 | 0.81 | XIAP (0.55) | XIAPBIRC2BIRC3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586542-B2 | Small molecule apoptosis promoters | JOYANT PHARMACEUTICALS, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120082640-A1 | Small molecule apoptosis promoters | JOYANT PHARMACEUTICALS, INC. | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120082640-A1 | Small molecule apoptosis promoters | BID, BAD, BAX | XIAP 31/4885ALDH1A1 4619/4885LMNA 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.