Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438390 | 0.80 | SIGMAR1 (0.49) | EPHX2KMT2ACNR1CNR2 | |
| SCHEMBL7438385 | 0.80 | SIGMAR1 (0.49) | EPHX2KMT2ACNR1CNR2 | |
| SCHEMBL8952256 | 0.79 | EPHX2 (0.41) | EPHX2KMT2AHSD11B1CNR1CNR2 | |
| SCHEMBL8952146 | 0.71 | SIGMAR1 (0.51) | EPHX2KMT2ACNR1CNR2FAAH | |
| SCHEMBL8952147 | 0.71 | SIGMAR1 (0.51) | EPHX2KMT2ACNR1CNR2FAAH | |
| SCHEMBL3073555 | 0.68 | SIGMAR1 (0.61) | EPHX2KMT2AHSD11B1 | |
| SCHEMBL19375483 | 0.68 | KMT2A (0.56) | EPHX2KMT2AHSD11B1FAAH | |
| SCHEMBL15051964 | 0.68 | KMT2A (0.65) | EPHX2KMT2AHSD11B1FAAH | |
| SCHEMBL1675682 | 0.68 | KMT2A (0.74) | EPHX2KMT2AHSD11B1CNR1CNR2 | |
| SCHEMBL3076737 | 0.67 | KMT2A (0.55) | EPHX2KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552443-A | TREATMENT OF PSYCHOSIS, ANXIETY AND AS HYPOTENSIVE AGENTS | OREGON HEALTH SCIENCES UNIVERSITY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5308869-A | TREATMENT OR PROPHYLAXIS OF ANXIETY IN AN ANIMAL | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION (US) | 1994-05-03 | — | — | US | disclosed |