SCHEMBL8952628

SCHEMBL8952628

CC(C)[Si](O[C@@H]1C(=O)NC1CC1CCCCC1)(C(C)C)C(C)C

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.37
MMP1 P03956 5/20 0.32
MMP9 P14780 4/20 0.32
MMP7 P09237 2/20 0.32
MMP3 P08254 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8952623 1.00 CTSD (0.37) CTSDMMP1MMP9MMP7MMP3
SCHEMBL5963946 1.00 CTSD (0.37) CTSDMMP1MMP9MMP7MMP3
SCHEMBL7732518 0.87 NAAA (0.33)
SCHEMBL9369598 0.87 NAAA (0.33)
SCHEMBL5963625 0.76 CTSD (0.36) CTSDMMP1MMP9MMP7MMP3
SCHEMBL7733379 0.75
SCHEMBL8397688 0.75 MAPT (0.31)
SCHEMBL9375081 0.71 HLCS (0.33)
SCHEMBL9274430 0.70 NAAA (0.34) CTSDMMP1MMP9MMP7MMP3
SCHEMBL5963363 0.66 CTSD (0.40) CTSDMMP1MMP9MMP7MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0690856-A4 UNIV NEW YORK (US) 1996-02-07 EP disclosed
EP-0690856-A1 ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1996-01-10 EP disclosed
WO-1994022856-A1 ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) 1994-10-13 WO disclosed