Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952869 | 0.85 | NR1I2 (0.42) | NR1I2NR4A2PDE4D | |
| SCHEMBL8952917 | 0.84 | NR1I2 (0.41) | NR1I2NR4A2PDE4D | |
| SCHEMBL8952807 | 0.83 | — | — | |
| SCHEMBL8952921 | 0.82 | NR1I2 (0.33) | NR1I2NR4A2PDE4DPRKAA2 | |
| SCHEMBL8952925 | 0.82 | NR1I2 (0.33) | NR1I2NR4A2PDE4DPRKAA2 | |
| SCHEMBL9562803 | 0.80 | HMGCR (0.34) | CTSA | |
| SCHEMBL9562819 | 0.80 | HMGCR (0.34) | CTSA | |
| SCHEMBL8952769 | 0.75 | ESR1 (0.39) | — | |
| SCHEMBL8953306 | 0.75 | CTSA (0.32) | CTSA | |
| SCHEMBL8952778 | 0.75 | ESR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506219-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-04-09 | — | — | US | disclosed |