Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952733 | 0.90 | TNF (0.46) | TNFNOTUMHTR6DCTPP1BRD4 | |
| SCHEMBL1080943 | 0.84 | TNF (0.47) | TNFHTR6DCTPP1BRD4LMNA | |
| SCHEMBL8952781 | 0.83 | KMT2A (0.45) | LMNATSHRSMN1; SMN2POLBKDM4E | |
| SCHEMBL8952676 | 0.83 | ALDH1A1 (0.52) | TNFHTR6DCTPP1BRD4LMNA | |
| SCHEMBL9212662 | 0.80 | PPARG (0.39) | TNFHTR6DCTPP1BRD4KDM4E | |
| SCHEMBL8953096 | 0.80 | PPARG (0.39) | TNFNOTUMHTR6BRD4KDM4E | |
| SCHEMBL1082621 | 0.77 | ALDH1A1 (0.51) | TNFHTR6DCTPP1BRD4LMNA | |
| SCHEMBL8952972 | 0.76 | GABRP (0.38) | SMN1; SMN2POLBKDM4EHPGDMEN1 | |
| SCHEMBL8953154 | 0.74 | KDM4E (0.45) | TSHRKDM4EKMT2A | |
| SCHEMBL7975722 | 0.73 | TNF (0.60) | TNFHTR6DCTPP1BRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523279-A | COMPOSITION FOR CONTROLLING MONOCOTYLEDENOUS AND DICOTYLEDENOUS PLANT SPECIES | AMERICAN CYANAMID COMPANY (US) | 1996-06-04 | — | — | US | disclosed |
| US-5516751-A | NONPHYTOTOXIC; SUGAR BEETS, SOYBEANS | AMERICAN CYANAMID COMPANY (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0474991-B1 | Herbicidal 2-(2-imidazolin -2-yl)-benzazoles | AMERICAN CYANAMID CO (US) | 1995-10-18 | — | — | EP | disclosed |
| US-5453415-A | To control monocotyledons and dicotyledones; apply to foilage, soil, or water containing seeds; pre-and post-emergence | AMERICAN CYANAMID COMPANY (US) | 1995-09-26 | — | — | US | disclosed |
| US-5300479-A | Pre-and postemergence herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| US-5108485-A | Controlling monocotyledonous and dicotyledonous plants | AMERICAN CYANAMID COMPANY (US) | 1992-04-28 | — | — | US | disclosed |
| EP-0474991-A1 | Herbicidal 2-(2-imidazolin -2-yl)-benzazoles | AMERICAN CYANAMID COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |