Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7510302 | 1.00 | KDM6B (0.51) | KDM6BALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL472283 | 1.00 | KDM6B (0.51) | KDM6BALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL10595550 | 0.85 | LDHA (0.56) | ALDH1A1KMT2AGAAL3MBTL1TSHR | |
| SCHEMBL10891346 | 0.84 | KDM6B (0.67) | KDM6BTSHRLMNAALBESR1 | |
| SCHEMBL7513061 | 0.82 | MEN1 (0.52) | KDM6BALDH1A1KMT2ATSHRCYP3A4 | |
| SCHEMBL8953404 | 0.82 | MEN1 (0.52) | KDM6BALDH1A1KMT2ATSHRCYP3A4 | |
| SCHEMBL10830533 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KMT2AL3MBTL1MAPK1ACACB | |
| SCHEMBL9424243 | 0.81 | HDAC1 (0.58) | ALDH1A1KMT2AGAAL3MBTL1TSHR | |
| SCHEMBL8953590 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KMT2AGAAL3MBTL1TSHR | |
| SCHEMBL599748 | 0.80 | SLC7A5 (0.62) | ALDH1A1KMT2ACYP3A4TDP1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514773-A | PARASITICIDES, ANTHELMINTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |