Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237591 | 0.86 | TBXAS1 (0.59) | TBXAS1HPGDTSHRCYP3A4ACE | |
| SCHEMBL10595550 | 0.85 | LDHA (0.56) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL19334004 | 0.82 | ALDH1A1 (0.48) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL9718459 | 0.82 | TBXAS1 (0.50) | ALDH1A1KMT2ATBXAS1L3MBTL1HPGD | |
| SCHEMBL11849471 | 0.82 | TBXAS1 (0.47) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL7510302 | 0.81 | KDM6B (0.51) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8953579 | 0.81 | KDM6B (0.51) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL472283 | 0.81 | KDM6B (0.51) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL19553694 | 0.80 | PTGS1 (0.66) | TBXAS1TSHRPTGS1PTGS2LMNA | |
| SCHEMBL599748 | 0.80 | SLC7A5 (0.62) | ALDH1A1KMT2AACACBCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312828-A | Substituted imidazoles having angiotensin II receptor blocking activity | SMITHKLINE BEECHAM CORPORATION A CORP. OF PENNSYLVANIA | 1994-05-17 | — | — | US | disclosed |