Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953837 | 1.00 | ALOX5 (0.35) | ALOX5HTR1ADRD2HTR2ACCR2 | |
| SCHEMBL8953717 | 0.89 | — | — | |
| SCHEMBL8953680 | 0.88 | MTNR1A (0.34) | ALOX5CCR2 | |
| SCHEMBL8953684 | 0.88 | MTNR1A (0.34) | ALOX5CCR2 | |
| SCHEMBL8953666 | 0.85 | ALOX5 (0.37) | ALOX5HTR1ADRD2HTR2A | |
| SCHEMBL8953670 | 0.85 | ALOX5 (0.37) | ALOX5HTR1ADRD2HTR2A | |
| SCHEMBL8953870 | 0.81 | — | — | |
| SCHEMBL8953766 | 0.77 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL8953763 | 0.77 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL8953842 | 0.77 | ALOX5 (0.35) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484786-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |