Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953766 | 1.00 | ALOX5 (0.43) | ALOX5HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8953710 | 0.87 | PTGIR (0.35) | ALOX5HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8953684 | 0.87 | MTNR1A (0.34) | ALOX5MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL8953680 | 0.87 | MTNR1A (0.34) | ALOX5MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL8953694 | 0.81 | RAB9A (0.41) | ALDH1A1RAB9ANPC1 | |
| SCHEMBL8953698 | 0.81 | RAB9A (0.41) | ALDH1A1RAB9ANPC1 | |
| SCHEMBL8953792 | 0.80 | MTNR1A (0.35) | MTNR1AMTNR1BKDM4EALDH1A1RAB9A | |
| SCHEMBL8953733 | 0.77 | ALOX5 (0.35) | ALOX5 | |
| SCHEMBL8953837 | 0.77 | ALOX5 (0.35) | ALOX5 | |
| SCHEMBL8953786 | 0.76 | ALOX5 (0.44) | ALOX5MGLLPIP5K1CKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484786-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |