Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 10/20 | 0.32 |
| ▸ | IL17A | Q16552 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953705 | 0.90 | ALOX5 (0.36) | HDAC3HDAC1HDAC2RORCIL17A | |
| SCHEMBL8953855 | 0.87 | RORC (0.31) | RORC | |
| SCHEMBL8953917 | 0.74 | ALOX5 (0.38) | — | |
| SCHEMBL8953700 | 0.68 | ALOX5 (0.40) | RORC | |
| SCHEMBL8953733 | 0.68 | ALOX5 (0.35) | — | |
| SCHEMBL8953837 | 0.68 | ALOX5 (0.35) | — | |
| SCHEMBL8953842 | 0.67 | ALOX5 (0.35) | — | |
| SCHEMBL9259112 | 0.65 | ALOX5 (0.43) | — | |
| SCHEMBL8953851 | 0.64 | SLC2A1 (0.43) | — | |
| SCHEMBL8953717 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484786-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |