Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954000 | 0.85 | MAPT (0.37) | MAPTALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL8954020 | 0.83 | TSHR (0.38) | MAPTALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL8955737 | 0.80 | ABHD6 (0.41) | MAPTALDH1A1TSHRCYP3A4MEN1 | |
| SCHEMBL415571 | 0.78 | TDP1 (0.44) | MAPTALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL8954017 | 0.73 | MAPT (0.38) | MAPTALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL9804106 | 0.73 | MAPT (0.38) | MAPTALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL7128858 | 0.73 | MAOB (0.42) | MAPTALDH1A1TSHRCYP3A4GFER | |
| SCHEMBL15981416 | 0.71 | CYP3A4 (0.46) | MAPTALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL7124322 | 0.71 | MAPT (0.39) | MAPTALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL9172695 | 0.71 | TDP1 (0.43) | MAPTALDH1A1TSHRCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536584-A | SEMICONDUCTOR INTEGRATED CIRCUIT, TRANSISTOR AND A THIN FILM MULTILEVEL WIRING BOARD USES SURFACE PROTECTIVE COATING OF POLYIMIDE | HITACHI, LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5272247-A | Polyimide precursor, cured product thereof, and processes for producing them | HITACHI, LTD. (JP) | 1993-12-21 | — | — | US | disclosed |