Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 4/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710123 | 0.89 | F10 (0.37) | F10PLAUMMP1MMP9MMP13 | |
| SCHEMBL8954843 | 0.80 | MMP8 (0.38) | F10MMP8MMP3 | |
| SCHEMBL8954783 | 0.80 | F10 (0.49) | F10PLAU | |
| SCHEMBL8954645 | 0.80 | F10 (0.40) | F10PLAU | |
| SCHEMBL8954944 | 0.80 | CASR (0.38) | F10PLAUMMP8MMP3MMP13 | |
| SCHEMBL9710558 | 0.76 | MMP8 (0.38) | F10MMP8MMP3MMP1MMP9 | |
| SCHEMBL8954946 | 0.75 | F10 (0.45) | F10PLAU | |
| SCHEMBL8954799 | 0.75 | F10 (0.48) | F10PLAU | |
| SCHEMBL9665510 | 0.75 | F10 (0.38) | F10PLAU | |
| SCHEMBL8955009 | 0.74 | HTT (0.52) | F10PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518735-A | ANTICOAGULANTS ADMINISTERED BY MOUTH | PENTAPHARM AG (CH) | 1996-05-21 | — | — | US | disclosed |