Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | PLG | P00747 | 6/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | HPN | P05981 | 1/20 | 0.34 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.34 |
| ▸ | PROC | P04070 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954645 | 0.89 | F10 (0.40) | F10F2PLGST14PLAU | |
| SCHEMBL8954799 | 0.89 | F10 (0.48) | F10F2PLGST14PLAU | |
| SCHEMBL9710706 | 0.84 | OPRM1 (0.36) | F10 | |
| SCHEMBL9710123 | 0.81 | F10 (0.37) | F10F2PLGPLAUHPN | |
| SCHEMBL9710643 | 0.81 | MMP8 (0.40) | — | |
| SCHEMBL9666086 | 0.81 | F10 (0.42) | F10F2PLGST14PLAU | |
| SCHEMBL8954875 | 0.79 | F10 (0.44) | F10F2PLGST14PLAU | |
| SCHEMBL8954944 | 0.78 | CASR (0.38) | F10PLGPLAUHPN | |
| SCHEMBL8954856 | 0.78 | F10 (0.50) | F10F2PLGST14PLAU | |
| SCHEMBL8955038 | 0.77 | F10 (0.47) | F10F2PLGST14PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511347-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | Pentapharm A.G. (CH) | 1992-11-04 | — | — | EP | disclosed |
| WO-1992008709-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | PENTAPHARM AG (CH) | 1992-05-29 | — | — | WO | disclosed |