Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.37 |
| ▸ | PLG | P00747 | 2/20 | 0.35 |
| ▸ | HPN | P05981 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954944 | 0.90 | CASR (0.38) | F10PLGHPNPLAUMMP13 | |
| SCHEMBL8954996 | 0.89 | F10 (0.39) | F10PLAUMMP1MMP9MMP13 | |
| SCHEMBL9710558 | 0.87 | MMP8 (0.38) | F10MMP1MMP9MMP13TBXA2R | |
| SCHEMBL8954799 | 0.81 | F10 (0.48) | F10PLGHPNPLAUF2 | |
| SCHEMBL9665510 | 0.81 | F10 (0.38) | F10PLGHPNPLAUF2 | |
| SCHEMBL9710706 | 0.79 | OPRM1 (0.36) | F10TBXA2RPOLBALDH1A1 | |
| SCHEMBL9710643 | 0.78 | MMP8 (0.40) | TBXA2RKAT6APOLBALDH1A1 | |
| SCHEMBL8954783 | 0.76 | F10 (0.49) | F10PLGHPNPLAUF2 | |
| SCHEMBL8954843 | 0.76 | MMP8 (0.38) | F10KAT6APOLBALDH1A1 | |
| SCHEMBL8954645 | 0.75 | F10 (0.40) | F10PLGPLAUF2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992008709-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | PENTAPHARM AG (CH) | 1992-05-29 | — | — | WO | disclosed |