Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9743230 | 0.99 | OPRK1 (0.67) | OPRK1OPRM1 | |
| SCHEMBL9669600 | 0.97 | OPRK1 (0.73) | OPRK1OPRM1 | |
| SCHEMBL9788886 | 0.97 | OPRK1 (0.73) | OPRK1OPRM1 | |
| SCHEMBL9669595 | 0.97 | OPRK1 (0.73) | OPRK1OPRM1 | |
| SCHEMBL9672001 | 0.96 | OPRK1 (0.72) | OPRK1OPRM1 | |
| Hydrochloric Acid SCHEMBL9742939 | 0.96 | OPRK1 (0.69) | OPRK1OPRM1 | |
| SCHEMBL9669607 | 0.83 | OPRM1 (0.59) | OPRK1OPRM1 | |
| SCHEMBL16237575 | 0.82 | OPRK1 (0.82) | OPRK1OPRM1 | |
| SCHEMBL17768434 | 0.82 | OPRK1 (0.82) | OPRK1OPRM1 | |
| SCHEMBL3765258 | 0.81 | OPRK1 (1.00) | OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306356-B1 | CONDENSED PIPERIDINE DERIVATIVES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION , THEIR USE AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-05-19 | — | — | EP | claimed |
| US-5126353-A | Also used as analgesics, diuretics, hypotensive agents, antiischemic agents | ROUSSEL UCLAF (FR) | 1992-06-30 | — | — | US | claimed |
| US-4927832-A | DIURETIC, ANTIARRYTHMIA, ANTIISCHEMIC, HYPOTENSIVE | ROUSSEL UCLAF (FR) | 1990-05-22 | — | — | US | claimed |
| EP-0306356-A1 | Condensed piperidine derivatives, intermediates and process for their preparation , their use as medicaments and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1989-03-08 | — | — | EP | claimed |
| EP-0456279-B1 | Condensed piperidine derivatives, intermediates and process for their preparation, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1996-01-03 | — | — | EP | disclosed |
| EP-0306356-B1 | CONDENSED PIPERIDINE DERIVATIVES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION , THEIR USE AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-05-19 | — | — | EP | disclosed |
| US-5126353-A | Also used as analgesics, diuretics, hypotensive agents, antiischemic agents | ROUSSEL UCLAF (FR) | 1992-06-30 | — | — | US | disclosed |
| EP-0456279-A1 | Condensed piperidine derivatives, intermediates and process for their preparation, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1991-11-13 | — | — | EP | disclosed |
| US-4927832-A | DIURETIC, ANTIARRYTHMIA, ANTIISCHEMIC, HYPOTENSIVE | ROUSSEL UCLAF (FR) | 1990-05-22 | — | — | US | disclosed |
| EP-0306356-A1 | Condensed piperidine derivatives, intermediates and process for their preparation , their use as medicaments and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1989-03-08 | — | — | EP | disclosed |