SCHEMBL9669607

SCHEMBL9669607

O=C(Cc1ccc(Cl)c(Cl)c1)N1CCCC2CC(N3CCCC3)CCC21

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 5/20 0.59
OPRK1 P41145 5/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9672127 0.84 NPC1 (0.47) OPRM1OPRK1
SCHEMBL8955239 0.83 OPRK1 (0.69) OPRM1OPRK1
Hydrochloric Acid SCHEMBL9743230 0.82 OPRK1 (0.67) OPRM1OPRK1
SCHEMBL9669600 0.81 OPRK1 (0.73) OPRM1OPRK1
SCHEMBL9669595 0.81 OPRK1 (0.73) OPRM1OPRK1
SCHEMBL9670674 0.81 HCRTR1 (0.48) OPRM1OPRK1
SCHEMBL9788886 0.81 OPRK1 (0.73) OPRM1OPRK1
SCHEMBL9670936 0.81 OPRD1 (0.54)
Hydrochloric Acid SCHEMBL9742939 0.81 OPRK1 (0.69) OPRM1OPRK1
SCHEMBL9672001 0.81 OPRK1 (0.72) OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0233793-B1 DECAHYDROQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1992-04-01 EP claimed