SCHEMBL8955266

SCHEMBL8955266

C=C(C)C(=O)OCCOC(=O)NC[SiH2]C

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.49
TSHR P16473 3/20 0.43
ACHE P22303 8/20 0.38
ALDH1A1 P00352 2/20 0.38
APEX1 P27695 2/20 0.34
POLB P06746 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
EPHX1 P07099 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13750209 0.83 THRB (0.46) THRBTSHRACHEALDH1A1APEX1
SCHEMBL19885344 0.82 THRB (0.55) THRBTSHRACHEALDH1A1APEX1
SCHEMBL30488753 0.82 THRB (0.55) THRBTSHRACHEALDH1A1
SCHEMBL890339 0.80 THRB (0.58) THRBTSHRACHEALDH1A1
SCHEMBL2403793 0.80 THRB (0.53) THRBTSHRACHEALDH1A1
SCHEMBL13872030 0.80 THRB (0.53) THRBTSHRACHEALDH1A1
SCHEMBL8955311 0.80 THRB (0.42) THRBTSHRALDH1A1APEX1POLB
SCHEMBL28138112 0.79 THRB (0.71) THRBTSHRALDH1A1APEX1POLB
SCHEMBL14008802 0.79 THRB (0.56) THRBTSHRACHEALDH1A1APEX1
SCHEMBL13872032 0.79 ACHE (0.58) THRBTSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8322869-B2 Optical film, polarizing plate, and image display apparatus FUJIFILM CORPORATION (JP) 2012-12-04 US disclosed
US-8187704-B2 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
US-8092872-B2 Optical film, antireflection film, and polarizing plate and display device using the same FUJIFILM CORPORATION (JP) 2012-01-10 US disclosed
US-7982953-B2 Antireflection film, and polarizing plate and image display device using the same FUJIFILM CORPORATION (JP) 2011-07-19 US disclosed
US-7968181-B2 Antireflection film and polarizing plate and image display device using same FUJIFILM CORPORATION (JP) 2011-06-28 US disclosed
US-7960018-B2 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2011-06-14 US disclosed
US-20100304123-A1 Antireflection film and polarizing plate and image display device using same FUJIFILM CORPORATION (JP) 2010-12-02 US disclosed
US-7622194-B2 use of a transparent support having specific physical properties during the spreading of a functional layer makes it possible to control the spread and the penetration of solvent and hence provide a good quality optical film having little coating defects, reducing impact of residual solvent; LCDs FUJIFILM CORPORATION (JP) 2009-11-24 US disclosed
US-20090091835-A1 OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY APPARATUS FUJIFILM CORPORATION (JP) 2009-04-09 US disclosed
US-20090081447-A1 OPTICAL FILM, POLARIZING PLATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20080285133-A1 Antireflection Film, Production Method Thereof, Polarizing Plate Using the Antireflection Film and Image Display Device Using the Antireflection Film or Polarizing Plate FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080131674-A1 OPTICAL FILM, ANTIREFLECTION FILM, AND POLARIZING PLATE AND DISPLAY DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2008-06-05 US disclosed
US-20080013172-A1 Method for Producing Light-Scattering Film, Polarizer Comprising Light-Scattering Film, and Liquid-Crystal Display Device Comprising Polarizer FUJIFILM CORPORATION (JP) 2008-01-17 US disclosed
US-20070231566-A1 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
US-20070048457-A1 Producing method of film having coated layer, film having coated layer, optical film, polarizing plate and liquid crystal display FUJI FILM CORPORATION (JP) 2007-03-01 US disclosed
US-20070047087-A1 Optical film, polarizing plate and image display device FUJI PHOTO FILM CO., LTD. (JP) 2007-03-01 US disclosed