Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20089019 | 0.95 | THRB (0.62) | THRBTSHRCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18123490 | 0.93 | TSHR (0.62) | THRBTSHRCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30488753 | 0.86 | THRB (0.55) | THRBTSHRACHEALDH1A1 | |
| SCHEMBL19885344 | 0.86 | THRB (0.55) | THRBTSHRCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL890335 | 0.85 | ACHE (0.56) | THRBTSHRCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13955819 | 0.85 | THRB (0.51) | THRBTSHRCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13872030 | 0.85 | THRB (0.53) | THRBTSHRACHEALDH1A1 | |
| SCHEMBL11544171 | 0.85 | THRB (0.44) | THRBTSHRCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2403793 | 0.85 | THRB (0.53) | THRBTSHRACHEALDH1A1 | |
| SCHEMBL16674069 | 0.83 | ACHE (0.60) | CHRNB2CHRNB4CHRNA3CHRNA4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250009608-A1 | Radically Polymerizable Materials For The Production Of Dental Moldings With High Fracture Toughness | IVOCLAR VIVADENT AG (LI) | 2025-01-09 | — | — | US | disclosed |
| US-20250002631-A1 | Radically Polymerizable Materials For The Production Of Dental Molding With Little Discoloration | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2025-01-02 | — | — | US | disclosed |
| EP-4484436-A1 | RADICAL POLYMERISABLE MATERIALS FOR PRODUCING DENTAL MOULDED BODIES WITH LOW DISCOLORATION | Ivoclar Vivadent AG (LI) | 2025-01-01 | — | — | EP | disclosed |
| EP-4483860-A1 | RADICALLY POLYMERISABLE MATERIALS FOR PRODUCING DENTAL MOULDED BODIES WITH HIGH FRACTURE TOUGHNESS | Ivoclar Vivadent AG (LI) | 2025-01-01 | — | — | EP | disclosed |
| US-11786444-B2 | Dental polyfunctional monomers and dental hydroxyl group-containing monomers | MITSUI CHEMICALS, INC. (JP) | 2023-10-17 | — | — | US | disclosed |
| US-20180110683-A1 | DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS | MITSUI CHEMICALS, INC. (JP) | 2018-04-26 | — | — | US | disclosed |
| EP-2578200-B1 | Compounds for infiltrating and/or sealing of dental hard substance and method | VOCO GMBH (DE) | 2018-03-28 | — | — | EP | disclosed |
| EP-2436365-B1 | Composite material comprising a monomer with a polyalicyclic structure element | VOCO GMBH (DE) | 2017-03-08 | — | — | EP | disclosed |
| EP-2436363-B1 | Compound comprising a monomer with a polyalicyclic structure element for filling and/or sealing a root canal | VOCO GMBH (DE) | 2017-01-18 | — | — | EP | disclosed |
| US-20160280807-A1 | PREPARATION OF NON-ISOCYANATE URETHANE (METH) ACRYLATES FOR URETHANE FUNCTIONAL LATEX | THE UNIVERSITY OF AKRON | 2016-09-29 | — | — | US | disclosed |
| US-20120083550-A1 | Composite Material Comprising a Monomer with a Polyalicyclic Structure Element as a Sealing Material | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120082954-A1 | Composition Comprising a Monomer with a Polyalicyclic Structure Element for Filling and/or Sealing a Root Canal | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120082954-A1 | Composition Comprising a Monomer with a Polyalicyclic Structure Element for Filling and/or Sealing a Root Canal | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120082637-A1 | Lacquer Composition Comprising a Monomer with a Polyalicyclic Structure Element | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| EP-2436668-A1 | Polymerisable compounds comprising a polyalicyclic structure element | VOCO GmbH (DE) | 2012-04-04 | — | — | EP | disclosed |
| US-20110265673-A1 | LITHOGRAPHIC PRINTING PLATE SUPPORT AND PRESENSITIZED PLATE | FUJIFILM CORPORATION (JP) | 2011-11-03 | — | — | US | disclosed |
| WO-2010042818-A1 | CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS | SEPTODONT CONFI-DENTAL DIVISION (US) | 2010-04-15 | — | — | WO | disclosed |
| US-20090246690-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20090246690-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |
| US-4165266-A | LIQUID MONOACRYLATE MONOMER AND A POLYVINYL ALKYL ETHER, QUICK STICKING | UNION CARBIDE CORPORATION (US) | 1979-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002631-A1 | Radically Polymerizable Materials For The Production Of Dental Molding With Little Discoloration | ORMDL3, ME1, MTR | THRB 4458/4885TSHR 3986/4885CHRNB2 4689/4885 |
| US-20250009608-A1 | Radically Polymerizable Materials For The Production Of Dental Moldings With High Fracture Toughness | RIF1, FANCI, MAT1A | THRB 3854/4885TSHR 4399/4885CHRNB2 4793/4885 |
| US-11786444-B2 | Dental polyfunctional monomers and dental hydroxyl group-containing monomers | PAM, CAD, FHIT | THRB 873/4885TSHR 2948/4885CHRNB2 2841/4885 |
| US-20120082637-A1 | Lacquer Composition Comprising a Monomer with a Polyalicyclic Structure Element | PELP1, ERCC1, GLRA1 | THRB 2532/4885TSHR 1595/4885CHRNB2 3305/4885 |
| US-20160280807-A1 | PREPARATION OF NON-ISOCYANATE URETHANE (METH) ACRYLATES FOR URETHANE FUNCTIONAL LATEX | ACR, MUS81, ALG3 | THRB 1879/4885TSHR 3505/4885CHRNB2 3518/4885 |
| US-20120083550-A1 | Composite Material Comprising a Monomer with a Polyalicyclic Structure Element as a Sealing Material | ERCC1, PARG, EPN1 | THRB 4507/4885TSHR 4875/4885CHRNB2 4322/4885 |
| US-20180110683-A1 | DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS | HRH3, HRH1, HRH2 | THRB 639/4885TSHR 861/4885CHRNB2 1070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.