Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.57 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729415 | 0.92 | BACE1 (0.67) | BACE1SLC6A11ANPEPBCHEATM | |
| SCHEMBL8731471 | 0.90 | BACE1 (0.55) | BACE1SLC6A11ANPEPBCHEATM | |
| SCHEMBL7306846 | 0.89 | BACE1 (0.60) | BACE1SLC6A11BCHE | |
| SCHEMBL7305633 | 0.89 | BACE1 (0.60) | BACE1SLC6A11BCHE | |
| SCHEMBL7610032 | 0.88 | BACE1 (0.71) | BACE1SLC6A11BCHE | |
| SCHEMBL7610027 | 0.88 | BACE1 (0.71) | BACE1SLC6A11BCHE | |
| SCHEMBL8732014 | 0.87 | BACE1 (0.55) | BACE1SLC6A11ANPEPBCHEATM | |
| SCHEMBL8734450 | 0.85 | BCHE (0.68) | BACE1SLC6A11ANPEPBCHEATM | |
| SCHEMBL8734455 | 0.84 | L3MBTL1 (0.52) | BACE1SLC6A11ANPEPBCHEATM | |
| SCHEMBL7647681 | 0.84 | L3MBTL1 (0.52) | BACE1SLC6A11ANPEPBCHEATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559256-A | Aminediol protease inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1996-09-24 | — | — | US | disclosed |