Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | CCR5 | P51681 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL15271605 | 0.98 | MMP2 (0.52) | MMP2TSHRHTTLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL16899244 | 0.98 | MMP2 (0.52) | MMP2TSHRHTTLMNAKDM4E | |
| Ether SCHEMBL15271604 | 0.88 | KMT2A (0.43) | MMP2TSHRHTTLMNAKDM4E | |
| SCHEMBL28067810 | 0.85 | LMNA (0.45) | MMP2TSHRHTTLMNAKDM4E | |
| SCHEMBL6222571 | 0.84 | LMNA (0.50) | MMP2TSHRHTTLMNAKDM4E | |
| SCHEMBL5307234 | 0.81 | P2RX7 (0.47) | MMP2TSHRHTTLMNAKDM4E | |
| SCHEMBL11973482 | 0.80 | LMNA (0.56) | MMP2TSHRHTTLMNAKDM4E | |
| SCHEMBL11497743 | 0.80 | NPC1 (0.47) | MMP2TSHRHTTLMNAKDM4E | |
| SCHEMBL7344355 | 0.79 | KDM4E (0.54) | MMP2TSHRHTTLMNAKDM4E | |
| SCHEMBL19303228 | 0.79 | KDM4E (0.54) | MMP2TSHRHTTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130701-A1 | 1-AMINOBENZO[4,5]IMIDAZO[1,2-A]PYRAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION THEREFOR AND USE THEREOF | 中山大学 | 2023-07-13 | — | — | WO | claimed |
| CN-114276354-A | 1-aminobenzo [4,5] imidazo [1,2-a ] pyrazine-3-formamide compound and preparation and application thereof | 中山大学 | 2022-04-05 | — | — | CN | claimed |
| CN-105601565-B | A kind of preparation method of the polyisocyanates of the biuret-containing structure of stable storage | 万华化学集团股份有限公司 | 2018-05-15 | — | — | CN | claimed |
| US-9737875-B2 | Affinity reagents for protein purification | IMPOSSIBLE FOODS INC. (US) | 2017-08-22 | — | — | US | claimed |
| CN-105601565-A | Method for preparing polyisocyanate containing biuret structure with stable storage | WANHUA CHEMICAL GROUP CO LTD | 2016-05-25 | — | — | CN | claimed |
| EP-0675111-A2 | Process for the preparation of 6-hydroxymethyl-quinolines | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-04 | — | — | EP | claimed |
| US-20250346563-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | UNIV TAIPEI MEDICAL (TW) | 2025-11-13 | — | — | US | disclosed |
| CN-118620179-A | Storage-stable biuret polyisocyanate composition and preparation method thereof | 万华化学集团股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| WO-2024086132-A1 | PROTACS TARGETING VIRAL ENZYMES FOR PRECISE TREATMENT OF COVID-19 | OHIO UNIVERSITY (US) | 2024-04-25 | — | — | WO | disclosed |
| CN-117887037-A | Biuret polyisocyanate composition and preparation method thereof | 万华化学（宁波）有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-117683205-A | Biuret polyisocyanate composition and preparation method thereof | 万华化学（宁波）有限公司 | 2024-03-12 | — | — | CN | disclosed |
| EP-3969446-B1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS INC (US) | 2023-09-27 | — | — | EP | disclosed |
| EP-3573960-B1 | N-{[2-(PIPERIDIN-1-YL)PHENYL](PHENYL)METHYL}-2-(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-YL)ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ROR-GAMMA MODULATORS FOR TREATING AUTOIMMUNE DISEASES | GENFIT (FR) | 2023-08-16 | — | — | EP | disclosed |
| EP-0675111-A2 | Process for the preparation of 6-hydroxymethyl-quinolines | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-04 | — | — | EP | disclosed |
| EP-0675111-A2 | Process for the preparation of 6-hydroxymethyl-quinolines | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-04 | — | — | EP | disclosed |
| US-5395838-A | Aromatic aminomethyl substitutes compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-03-07 | — | — | US | disclosed |
| EP-0373891-B1 | Anti-tumour agents | ICI PLC (GB) | 1994-11-02 | — | — | EP | disclosed |
| US-5252573-A | Quinazoline derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-12 | — | — | US | disclosed |
| US-5089499-A | Anticarcinogenic agents; thymidylate synthetase inhibitors; antiallergens; psoriasis | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-18 | — | — | US | disclosed |
| EP-0373891-A2 | Anti-tumour agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346563-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | HDAC1, HDAC3, HDAC5 | MMP2 167/4885TSHR 4209/4885HTT 1141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.