Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19612511 | 0.89 | MAPT (0.53) | LMNAMAPTMEN1KMT2ANR1I2 | |
| SCHEMBL6706652 | 0.85 | CYP1A2 (0.59) | MAPTMCHR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16417099 | 0.84 | CNR2 (0.55) | LMNAMAPTMEN1KMT2ANR1I2 | |
| SCHEMBL4743007 | 0.84 | HTR1B (0.59) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8542666 | 0.83 | LMNA (0.56) | LMNAMAPTMEN1KMT2ANR1I2 | |
| SCHEMBL8955641 | 0.82 | CNR2 (0.51) | MEN1KMT2ACNR1CNR2CYP1A2 | |
| SCHEMBL8778574 | 0.82 | MCHR1 (0.45) | LMNAMAPTMEN1KMT2ANR1I2 | |
| SCHEMBL8956316 | 0.82 | HTR1B (0.57) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL22207446 | 0.82 | CNR1 (0.48) | LMNAMAPTMEN1KMT2ANR1I2 | |
| SCHEMBL5411440 | 0.82 | ALDH1A1 (0.49) | LMNAMAPTMEN1KMT2ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |