Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.63 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.63 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12698684 | 0.88 | ALDH1A1 (0.67) | CYSLTR2CYSLTR1PPARGBRD4FAAH | |
| SCHEMBL3934739 | 0.87 | PPARA (0.74) | CYSLTR2CYSLTR1PPARAPPARGPLA2G4B | |
| SCHEMBL10054169 | 0.87 | L3MBTL1 (0.62) | CYSLTR2CYSLTR1BRD4FAAHALDH1A1 | |
| SCHEMBL3173429 | 0.85 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1BRD4FAAHTSHR | |
| SCHEMBL3937044 | 0.85 | SMPD1 (0.60) | CYSLTR2CYSLTR1PPARAPPARGPLA2G4B | |
| SCHEMBL2137203 | 0.84 | MAPK1 (0.66) | CYSLTR2CYSLTR1PPARAPPARGBRD4 | |
| SCHEMBL8279022 | 0.84 | TSHR (0.57) | CYSLTR2CYSLTR1PPARAPPARGBRD4 | |
| SCHEMBL987722 | 0.84 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1BRD4FAAHTSHR | |
| SCHEMBL853578 | 0.84 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PPARAPPARGBRD4 | |
| SCHEMBL13986590 | 0.84 | L3MBTL1 (0.59) | PPARAPPARGBRD4ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |