Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10054169 | 0.85 | L3MBTL1 (0.62) | CYSLTR2CYSLTR1BRD4FAAHNPC1 | |
| SCHEMBL6328915 | 0.85 | MRGPRX4 (0.52) | NPC1ALDH1A1PDE3BPDE3AP2RY12 | |
| SCHEMBL29198000 | 0.85 | BRD4 (0.51) | CYSLTR2CYSLTR1BRD4PDK2FAAH | |
| SCHEMBL12698684 | 0.84 | ALDH1A1 (0.67) | CYSLTR2CYSLTR1BRD4PDK2FAAH | |
| SCHEMBL8955658 | 0.84 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1BRD4PDK2FAAH | |
| SCHEMBL3173429 | 0.84 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1BRD4PDK2FAAH | |
| SCHEMBL913974 | 0.84 | PPARA (0.59) | NPC1ALDH1A1PPARGPPARA | |
| SCHEMBL8279022 | 0.83 | TSHR (0.57) | CYSLTR2CYSLTR1BRD4PDK2FAAH | |
| SCHEMBL2137203 | 0.83 | MAPK1 (0.66) | CYSLTR2CYSLTR1BRD4PDK2FAAH | |
| SCHEMBL987722 | 0.83 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1BRD4PDK2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867023-B2 | Production method of polyhydroxyalkanoate from substituted fatty acid ester as raw material | CANON KABUSHIKI KAISHA (JP) | 2005-03-15 | — | — | US | claimed |
| US-20020081646-A1 | Production method of polyhydroxyalkanoate form substituted fatty acid ester as raw material | CANON KABUSHIKI KAISHA (JP) | 2002-06-27 | — | — | US | claimed |
| EP-1201763-A2 | Production method of polyhydroxyalkanoate from substituted fatty acid ester as raw material | CANON KABUSHIKI KAISHA (JP) | 2002-05-02 | — | — | EP | claimed |
| EP-2875001-B1 | NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS | SUNSHINE LAKE PHARMA CO LTD (CN) | 2019-01-09 | — | — | EP | disclosed |
| US-20180346484-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBVIE DEUTSCHLAND (DE) | 2018-12-06 | — | — | US | disclosed |
| US-9879033-B2 | Modulators of 5-HT receptors and methods of use thereof | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-01-30 | — | — | US | disclosed |
| EP-2571353-B1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBVIE INC (US) | 2017-08-09 | — | — | EP | disclosed |
| US-9434695-B2 | Nitrogenous heterocyclic derivatives and their application in drugs | SUNSHINE LAKE PHARMA CO., LTD (CN) | 2016-09-06 | — | — | US | disclosed |
| CN-103570630-B | Nitrogen heterocyclic derivative and the application in medicine thereof | SUNSHINE LAKE PHARMA CO.,LTD. (CN) | 2016-04-20 | — | — | CN | disclosed |
| CN-105481864-A | Modulators of 5-HT receptors and methods of use thereof | ABBOTT GMBH & CO KG ABBOTT LAB | 2016-04-13 | — | — | CN | disclosed |
| US-20160096851-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBVIE INC. | 2016-04-07 | — | — | US | disclosed |
| US-6867023-B2 | Production method of polyhydroxyalkanoate from substituted fatty acid ester as raw material | CANON KABUSHIKI KAISHA (JP) | 2005-03-15 | — | — | US | disclosed |
| US-20040067576-A1 | Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same | CANON KABUSHIKI KAISHA (JP) | 2004-04-08 | — | — | US | disclosed |
| US-6649381-B1 | Biosynthesis of high purity polylactones | CANON KABUSHIKI KAISHA (JP) | 2003-11-18 | — | — | US | disclosed |
| US-20030208029-A1 | Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same | CANON KABUSHIKI KAISHA (JP) | 2003-11-06 | — | — | US | disclosed |
| US-6586562-B2 | Polylactone with units such as of 3-hydroxy-5-(4-fluorophenyl)valeric acid; biosynthesis of the polylactone by microorganism; Pseudomonas cichorii; P. putida; P. jessenii | CANON KABUSHIKI KAISHA (JP) | 2003-07-01 | — | — | US | disclosed |
| US-20020081646-A1 | Production method of polyhydroxyalkanoate form substituted fatty acid ester as raw material | CANON KABUSHIKI KAISHA (JP) | 2002-06-27 | — | — | US | disclosed |
| EP-1201763-A2 | Production method of polyhydroxyalkanoate from substituted fatty acid ester as raw material | CANON KABUSHIKI KAISHA (JP) | 2002-05-02 | — | — | EP | disclosed |
| US-20020022253-A1 | Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same | CANON KABUSHIKI KAISHA (JP) | 2002-02-21 | — | — | US | disclosed |
| EP-1113033-A2 | Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same | CANON KABUSHIKI KAISHA (JP) | 2001-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096851-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | HTR3A, HTR5A, HTR3C | CYSLTR2 191/4885CYSLTR1 189/4885BRD4 2085/4885 |
| US-20020081646-A1 | Production method of polyhydroxyalkanoate form substituted fatty acid ester as raw material | FASN, FFAR1, ACADM | CYSLTR2 602/4885CYSLTR1 463/4885BRD4 4370/4885 |
| US-20180346484-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | HTR3A, HTR5A, HTR3C | CYSLTR2 191/4885CYSLTR1 189/4885BRD4 2085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.