Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.67 |
| ▸ | CNR2 | P34972 | 3/20 | 0.65 |
| ▸ | HTR1B | P28222 | 7/20 | 0.64 |
| ▸ | HTR1D | P28221 | 2/20 | 0.64 |
| ▸ | CNR1 | P21554 | 2/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 2/20 | 0.57 |
| ▸ | HTR6 | P50406 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438840 | 1.00 | KCNA3 (0.67) | KCNA3CNR2HTR1BHTR1DCNR1 | |
| SCHEMBL1007097 | 1.00 | KCNA3 (0.67) | KCNA3CNR2HTR1BHTR1DCNR1 | |
| SCHEMBL4647042 | 1.00 | KCNA3 (0.67) | KCNA3CNR2HTR1BHTR1DCNR1 | |
| SCHEMBL8544058 | 1.00 | KCNA3 (0.67) | KCNA3CNR2HTR1BHTR1DCNR1 | |
| SCHEMBL6272756 | 0.98 | KCNA3 (0.69) | KCNA3CNR2HTR1BHTR1DCNR1 | |
| SCHEMBL3607496 | 0.93 | HTR1B (0.68) | KCNA3CNR2HTR1BHTR1DCNR1 | |
| Hydrochloric Acid SCHEMBL28443504 | 0.91 | HTR1B (0.66) | KCNA3CNR2HTR1BHTR1DCNR1 | |
| SCHEMBL16902853 | 0.91 | KCNA3 (0.79) | KCNA3HTR1BHTR1DSLC6A4HRH1 | |
| SCHEMBL16902840 | 0.91 | KCNA3 (0.79) | KCNA3HTR1BHTR1DSLC6A4HRH1 | |
| SCHEMBL16902854 | 0.91 | KCNA3 (0.79) | KCNA3HTR1BHTR1DSLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |
| EP-0225011-A1 | Pesticidal (1'-naphthyloxy)-alkene (or -alkadiene)-carboxylic-acid amides | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-06-10 | — | — | EP | disclosed |