SCHEMBL6438840

SCHEMBL6438840

OCCCCCCCCOc1cccc2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.67
CNR2 P34972 3/20 0.65
HTR1B P28222 7/20 0.64
HTR1D P28221 2/20 0.64
CNR1 P21554 2/20 0.62
SLC6A4 P31645 2/20 0.61
HRH1 P35367 1/20 0.58
HRH3 Q9Y5N1 4/20 0.57
HTR2A P28223 2/20 0.57
HTR7 P34969 2/20 0.57
HTR6 P50406 2/20 0.57
TDP1 Q9NUW8 1/20 0.56
KDM4E B2RXH2 2/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
ALDH1A1 P00352 1/20 0.55
CYP1A2 P05177 1/20 0.54
CYP2C19 P33261 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8955863 1.00 KCNA3 (0.67) KCNA3CNR2HTR1BHTR1DCNR1
SCHEMBL1007097 1.00 KCNA3 (0.67) KCNA3CNR2HTR1BHTR1DCNR1
SCHEMBL4647042 1.00 KCNA3 (0.67) KCNA3CNR2HTR1BHTR1DCNR1
SCHEMBL8544058 1.00 KCNA3 (0.67) KCNA3CNR2HTR1BHTR1DCNR1
SCHEMBL6272756 0.98 KCNA3 (0.69) KCNA3CNR2HTR1BHTR1DCNR1
SCHEMBL3607496 0.93 HTR1B (0.68) KCNA3CNR2HTR1BHTR1DCNR1
Hydrochloric Acid SCHEMBL28443504 0.91 HTR1B (0.66) KCNA3CNR2HTR1BHTR1DCNR1
SCHEMBL16902853 0.91 KCNA3 (0.79) KCNA3HTR1BHTR1DSLC6A4HRH1
SCHEMBL16902840 0.91 KCNA3 (0.79) KCNA3HTR1BHTR1DSLC6A4HRH1
SCHEMBL16902854 0.91 KCNA3 (0.79) KCNA3HTR1BHTR1DSLC6A4HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1294674-B1 NAPHTHYLOXYALKYL (METH) ACRYLATES WITH HIGH REFRACTIVE INDICES AND LOW GLASS TRANSITION TEMPERATURES 3M INNOVATIVE PROPERTIES CO (US) 2005-11-09 EP disclosed
EP-1294674-A1 NAPHTHYLOXYALKYL (METH) ACRYLATES WITH HIGH REFRACTIVE INDICES AND LOW GLASS TRANSITION TEMPERATURES 3M Innovative Properties Company (US) 2003-03-26 EP disclosed
US-6433216-B1 FOR PRODUCING POLYMERS USED IN OPTICAL ELEMENTS, FOR REDUCING GLARE ON SUBSTRATE USING POLYMER 3M INNOVATIVE PROPERTIES COMPANY 2002-08-13 US disclosed
US-20020058773-A1 NAPHTHYLOXYALKYL(METH)ACRYLATES WITH HIGH REFRACTIVE INDICES AND LOW GLASS TRANSITION TEMPERATURES 3M INNOVATIVE PROPERTIES COMPANY 2002-05-16 US disclosed
US-6376704-B1 Naphthyoxyalkyl(meth)acrylates with high refractive indices and low glass transition temperatures 3M INNOVATIVE PROPERTIES COMPANY 2002-04-23 US disclosed
WO-2002000594-A9 NAPHTHYLOXYALKYL (METH) ACRYLATES WITH HIGH REFRACTIVE INDICES AND LOW GLASS TRANSITION TEMPERATURES 3M INNOVATIVE PROPERTIES CO (US) 2002-03-14 WO disclosed
WO-2002000594-A1 NAPHTHYLOXYALKYL (METH) ACRYLATES WITH HIGH REFRACTIVE INDICES AND LOW GLASS TRANSITION TEMPERATURES 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058773-A1 NAPHTHYLOXYALKYL(METH)ACRYLATES WITH HIGH REFRACTIVE INDICES AND LOW GLASS TRANSITION TEMPERATURES VIM, MSN, NECTIN4 KCNA3 1935/4885CNR2 3904/4885HTR1B 2843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.