Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2085224 | 0.86 | L3MBTL1 (0.62) | ALDH1A1KDM4ERAB9ANPC1MAPT | |
| SCHEMBL571251 | 0.85 | CTBP2 (0.56) | ALDH1A1KDM4ERAB9ANPC1PTPN1 | |
| SCHEMBL29256169 | 0.83 | NPC1 (0.56) | RAB9ANPC1MAPTSMN1; SMN2SHBG | |
| SCHEMBL7264886 | 0.83 | RAB9A (0.47) | RAB9ANPC1MAPTSMN1; SMN2SHBG | |
| SCHEMBL27917765 | 0.83 | ALDH1A1 (0.51) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL2083626 | 0.82 | KCNJ5 (0.63) | ALDH1A1RAB9ANPC1PTPN1MAPT | |
| SCHEMBL3097072 | 0.80 | MEN1 (0.47) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 | |
| SCHEMBL11000136 | 0.80 | ERCC1 (0.48) | ALDH1A1RAB9ANPC1PTPN1MAPT | |
| SCHEMBL31201903 | 0.79 | CYP3A4 (0.53) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL1121619 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4ERAB9ANPC1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103936552-A | Preparation method of epoxiconazole intermediate (Z)-2-(4-fluorophenyl)-1-(2-chlorphenyl)-3-halogen propylene | SINOCHEM CORP | 2014-07-23 | — | — | CN | disclosed |
| US-5532374-A | Method of preparation of bis-quinolines | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5436242-A | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof for inhibiting blood platelet aggregation | SANKYO COMPANY, LIMITED (JP) | 1995-07-25 | — | — | US | disclosed |
| US-5288726-A | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation | UBE INDUSTRIES LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0542411-A2 | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation | Sankyo Company Limited (JP) | 1993-05-19 | — | — | EP | disclosed |