SCHEMBL8956441

SCHEMBL8956441

Clc1ccc(C=Cc2nnc(C(Cl)(Cl)Cl)o2)c(Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 2/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ METAP2 P50579 1/20 0.39
▸ MAPT P10636 5/20 0.39
▸ KDM4E B2RXH2 3/20 0.39
▸ MEN1 O00255 3/20 0.39
▸ LMNA P02545 3/20 0.39
▸ KMT2A Q03164 3/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ GAA P10253 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ ALPL P05186 1/20 0.39
▸ GLA P06280 1/20 0.39
▸ ALPG P10696 1/20 0.39
▸ PKM P14618 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ TDP1 Q9NUW8 2/20 0.39
▸ TNF P01375 1/20 0.38
▸ NOD1 Q9Y239 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8956554 0.82 CASP3 (0.41) METAP2MAOB
SCHEMBL12196223 0.82 METAP2 (0.38) METAP2KDM4EMEN1KMT2AALDH1A1
SCHEMBL13578693 0.79 METAP2 (0.34) METAP2MAPTKDM4EMEN1LMNA
SCHEMBL28838566 0.79 NPC1 (0.43) NPC1RAB9AMETAP2MAPTKDM4E
SCHEMBL28838565 0.79 NPC1 (0.43) NPC1RAB9AMETAP2MAPTKDM4E
SCHEMBL195259 0.78 METAP2 (0.46) NPC1RAB9AMETAP2MAPTKDM4E
SCHEMBL195260 0.78 METAP2 (0.46) NPC1RAB9AMETAP2MAPTKDM4E
SCHEMBL13578474 0.78 SLC2A1 (0.35) NPC1RAB9AMETAP2MAPTKDM4E
SCHEMBL195495 0.70 HPGD (0.49) NPC1RAB9AMAPTKDM4EMEN1
SCHEMBL195496 0.70 HPGD (0.49) NPC1RAB9AMAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8400592-B2 Polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2013-03-19 — — US disclosed
US-8400592-B2 Polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2013-03-19 — — US disclosed
US-8304025-B2 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2012-11-06 — — US disclosed
US-8304025-B2 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2012-11-06 — — US disclosed
US-8241740-B2 Layer laminated to support; ionization radiation; curing using free radical catalyst; image display and polarization plates FUJIFILM CORPORATION (JP) 2012-08-14 — — US disclosed
US-8241740-B2 Layer laminated to support; ionization radiation; curing using free radical catalyst; image display and polarization plates FUJIFILM CORPORATION (JP) 2012-08-14 — — US disclosed
US-8187704-B2 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2012-05-29 — — US disclosed
US-8187704-B2 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2012-05-29 — — US disclosed
US-8047662-B2 Antiglare film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2011-11-01 — — US disclosed
US-8047662-B2 Antiglare film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2011-11-01 — — US disclosed
US-20080069975-A1 Optical film FUJIFILM CORPORATION (JP) 2008-03-20 — — US disclosed
US-20080069975-A1 Optical film FUJIFILM CORPORATION (JP) 2008-03-20 — — US disclosed
US-20070291363-A1 Optical Film FUJIFILM CORPORATION (JP) 2007-12-20 — — US disclosed
US-20070291363-A1 Optical Film FUJIFILM CORPORATION (JP) 2007-12-20 — — US disclosed
US-20070243370-A1 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-10-18 — — US disclosed
US-20070243370-A1 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-10-18 — — US disclosed
US-20070231566-A1 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2007-10-04 — — US disclosed
US-20070231566-A1 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2007-10-04 — — US disclosed
US-20070104896-A1 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-05-10 — — US disclosed
US-20070104896-A1 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-05-10 — — US disclosed
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