SCHEMBL8956458

SCHEMBL8956458

O=[N+]([O-])c1ccc(C=Cc2nnc(C(Cl)(Cl)Cl)o2)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ METAP2 P50579 1/20 0.50
▸ MAPT P10636 3/20 0.49
▸ NPC1 O15118 3/20 0.49
▸ RAB9A P51151 3/20 0.49
▸ APP P05067 2/20 0.45
▸ FBP1 P09467 1/20 0.44
▸ PTGS2 P35354 6/20 0.43
▸ PTGS1 P23219 2/20 0.43
▸ CYP19A1 P11511 2/20 0.43
▸ SMN1; SMN2 Q16637 3/20 0.43
▸ MEN1 O00255 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ HPGD P15428 1/20 0.43
▸ MAPK1 P28482 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11133082 0.85 MAPT (0.61) METAP2MAPTNPC1RAB9AAPP
SCHEMBL11133083 0.85 MAPT (0.61) METAP2MAPTNPC1RAB9AAPP
SCHEMBL321610 0.79 HPGD (0.48) MAPTNPC1RAB9ASMN1; SMN2MEN1
SCHEMBL321609 0.79 HPGD (0.48) MAPTNPC1RAB9ASMN1; SMN2MEN1
SCHEMBL195260 0.79 METAP2 (0.46) METAP2MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL14874539 0.78 METAP2 (0.53) METAP2MAPTNPC1RAB9AAPP
SCHEMBL14874538 0.78 METAP2 (0.53) METAP2MAPTNPC1RAB9AAPP
SCHEMBL126560 0.78 MAOB (0.45) MAPTNPC1RAB9AAPPPTGS2
SCHEMBL9687509 0.78 KDM4E (0.58) METAP2MAPTNPC1RAB9APTGS2
SCHEMBL126561 0.78 MAOB (0.45) MAPTNPC1RAB9AAPPPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8400592-B2 Polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2013-03-19 — — US disclosed
US-8400592-B2 Polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2013-03-19 — — US disclosed
US-8304025-B2 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2012-11-06 — — US disclosed
US-8304025-B2 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2012-11-06 — — US disclosed
US-8241740-B2 Layer laminated to support; ionization radiation; curing using free radical catalyst; image display and polarization plates FUJIFILM CORPORATION (JP) 2012-08-14 — — US disclosed
US-8241740-B2 Layer laminated to support; ionization radiation; curing using free radical catalyst; image display and polarization plates FUJIFILM CORPORATION (JP) 2012-08-14 — — US disclosed
US-8187704-B2 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2012-05-29 — — US disclosed
US-8187704-B2 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2012-05-29 — — US disclosed
EP-0949540-B1 Method for producing lithographic printing plate suitable for laser scan exposure, and photopolymerizable composition FUJIFILM CORP (JP) 2012-05-02 — — EP disclosed
US-8047662-B2 Antiglare film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2011-11-01 — — US disclosed
US-20070291363-A1 Optical Film FUJIFILM CORPORATION (JP) 2007-12-20 — — US disclosed
US-20070291363-A1 Optical Film FUJIFILM CORPORATION (JP) 2007-12-20 — — US disclosed
US-20070243370-A1 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-10-18 — — US disclosed
US-20070243370-A1 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-10-18 — — US disclosed
US-20070231566-A1 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2007-10-04 — — US disclosed
US-20070231566-A1 Optical film, polarizing plate, image display, and manufacturing method of optical film FUJIFILM CORPORATION (JP) 2007-10-04 — — US disclosed
US-20070104896-A1 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-05-10 — — US disclosed
US-20070104896-A1 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-05-10 — — US disclosed
US-20070092836-A1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2007-04-26 — — US disclosed
US-20070092836-A1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2007-04-26 — — US disclosed
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